ECT in depression

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ECT and rTMS for depression.

Schulze-Rauschenbach et al (2005) report an interesting study comparing electroconvulsive therapy (ECT) with repetitive transcranial magnetic stimulation (rTMS) for the treatment of major depression. They conclude that both are equally efficacious, but rTMS is associated with fewer cognitive side-effects. Ultimately, a therapeutic plan that optimally helps a given individual cope with disabilit...

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Ketamine Effective in ECT-Resistant Depression

In an abstract presented at the Society of Biological Psychiatry meeting in May, Lobna Ibrahim and Carlos Zarate of the National Institute of Mental Health reported that intravenous infusions of ketamine were effective in a majority of patients with highly treatment-resistant depression, i.e. even those who had been unresponsive to a course of electroconvulsive therapy. Editor’s note: Few treat...

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Ameliorative activity of co-administration of ketamine and ECT on depression like behaviors in depressed rats

Background and Objective: Electroconvulsive therapy (ECT) is the end choice treatment for patients with major depressive disorder (MDD). Regarding researches that show NMDA receptor inactivation could yield the same results as anti-depressant drugs, however, the present study examined co-administration of ECT and ketamine (as NMDA antagonist) on depressed rat behaviors.   Materials and Methods...

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Clinical Predictors of Response to Ect in Severe Depression

Sir, I read with interest the article by Gupta et al. (2000, 60-65). The authors administered 6 electro-convulsive therapy (ECT), over 2 week period, in an uncontrolled open manner on a purposively selected sample of antidepressant naive or antidepressant free patients (N=22) of Severe Depressive Episode with the objective to ascertain which of the selected socioderrographic and clinical variab...

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Ect and Platelet 5ht Uptake in Major Depression

Several studies have reported decreased platelet 5-HT uptake in patients of major depression. The mechanism of antidepressant action of ECT is not clear. The present work was undertaken with the aim to study the active platelet 5-HT uptake and the effect of ECT on it in patients of major depression. 15 patients of major depression (DSM-lll-R) and equal number of age and sex-matched controls wer...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2005

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.187.5.487